The Institute’s director is Alan S. Wayne, MD, who joined CHLA and the University of Southern California (USC) in July 2013. 2012; 7(12):e52655. 2012 Feb 23; 119(8):1848-55. . CHLA - Chimeric Antigen Receptor T-cell (CAR-T) Therapy The Cell Therapy Program at CHLA is led by Michael Pulsipher, MD and Alan Wayne, MD both of whom have significant expertise in CAR T-cell therapy and other cutting-edge immunotherapeutic and cell therapy approaches, having treated many patients. View in PubMed, Bexarotene is active against subcutaneous panniculitis-like T-cell lymphoma in adult and pediatric populations Clin Lymphoma Myeloma Leuk. Find a Doctor 2017 Sep 10; 9(9). View in PubMed, Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans Blood. 2015 Mar; 168(6):865-73. . For more information, please contact our New Referrals Office. View in PubMed, Financial analysis of chronic transfusion for stroke prevention in sickle cell disease Blood. 2013 Mar; 33(3):e19-22. I also oversee our education programs that includes students at stages of training ranging from high school to post-doctoral.” “I offer my unreserved recommendation for his application” Alan S. … CHLA is the only approved center in Southern California, having played a pivotal role in the two multicenter trials leading to approval. Alan S. Wayne, M.D. . View in PubMed, A phase 1 study of azacitidine combined with chemotherapy in childhood leukemia: a report from the TACL consortium Blood. Alan S. Wayne, MD, is the Director of the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles and serves as head of the Division of Hematology, Oncology and Blood and Marrow Transplantation in the Department of Pediatrics. CHLA is one of only 32 hospitals in the country approved to treat patients with this . . 2010 Jan; 54(1):173-5. . View in PubMed, Elevation of soluble CD307 (IRTA2/FcRH5) protein in the blood and expression on malignant cells of patients with multiple myeloma, chronic lymphocytic leukemia, and mantle cell lymphoma Leukemia. View in PubMed, NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: report from the Committee on Disease-Specific Methods and Strategies for Monitoring Relapse following Allogeneic Stem Cell TransplantationPart I: Methods, acute leukemias, and myelodysplastic syndromes. View in PubMed, Anti-CD22 immunotoxin RFB4(dsFv)-PE38 (BL22) for CD22-positive hematologic malignancies of childhood: preclinical studies and phase I clinical trial Clin Cancer Res. The approach is called CAR-T therapy, and it uses a patient’s own white blood cells that have been genetically re-engineered to specifically target and kill cancer cells. View in PubMed, Bortezomib, Dexamethasone, Mitoxantrone, and Vinorelbine (BDMV): An Active Reinduction Regimen for Children With Relapsed Acute Lymphoblastic Leukemia and Asparaginase Intolerance J Pediatr Hematol Oncol. Biol Blood Marrow Transplant. “I am writing to offer my strongest possible recommendation in support of Caleb Moss” “I am the physician in charge of the pediatric cancer and blood diseases program at Children’s Hospital Los Angeles (CHLA) and the University of Southern California. View in PubMed, The American Society of Pediatric Hematology/Oncology workforce assessment: Part 1-Current state of the workforce Pediatr Blood Cancer. View in PubMed, High frequencies of leukemia stem cells in poor-outcome childhood precursor-B acute lymphoblastic leukemias Leukemia. . 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